Save up -80% on Abacavir

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Ziagen

$79.5160 tablets/300mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Abacavir coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Abacavir every time. What are you waiting for? Claim your prescription drug card now!

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Abacavir volume of distribution

The apparent volume of distribution of abacavir after intravenous administration is approximately 0.86 +/- 0.15 L/kg, suggesting that abacavir is distributed to extravascular spaces.

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About RX24Drugs

2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Abacavir

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. (Wikipedia) Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.

Abacavir mechanism of action

Abacavir is a carbocyclic synthetic nucleoside analogue and an antiviral agent. Intracellularly, abacavir is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5′-triphosphate (dGTP). Carbovir triphosphate inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA. Viral DNA growth is terminated because the incorporated nucleotide lacks a 3′-OH group, which is needed to form the 5 to 3 phosphodiester linkage essential for DNA chain elongation.

Dosage forms of Abacavir

Abacavir Sulphate300mg60 Tablet$285.00
Abacavir Sulphate300mg90 Tablet$423.00
Ziagen Solution20mg/mL240mL Oral Solution$159.00
Ziagen300mg60 Tablet$450.00
Abacavir/Lamivudine600/300mg30 Tablet$297.00
Trizivir300/150/300mg60 Tablet$1,550.00

Prescription Generics


International Brands



{(1S-cis)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl}methanol Abacavir


Camber Pharmaceuticals, Inc.

CAS number






Affected organisms

Human Immunodeficiency Virus

Indication of Abacavir

For the treatment of HIV-1 infection, in combination with other antiretroviral agents.

Toxicity of Abacavir

Some myocardial degeneration has been noticed in rats and mice. The most commonly reported adverse reactions of at least moderate intensity (incidence 10%) in adult HIV-1 clinical trials were nausea, headache, malaise and fatigue, nausea and vomiting, and dreams/sleep disorders. Serious hypersensitivity reactions have been associated with abacavir which has been strongly linked to the presence of the HLA-B*57:01 allele. This reaction manifests itself in patients within the first 6 weeks of treatment. Patients should be tested for the presence of this allele as recommended by the U.S Food and Drug Administration (FDA).

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