Save up -80% on Acamprosate
Note: this is a drug discount program, not an insurance plan.
2018 Price of Acamprosate
Campral 333 mg dose pak
* price without discount in nearest pharmacy. Price may vary.
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Acamprosate volume of distribution
* 72 to 109 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Acamprosate
Acamprosate, also known by the brand name Campraltrade;, is a drug used for treating alcohol dependence. Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be disrupted by alcoholism, possibly by blocking glutaminergic N-methyl-D-aspartate receptors, while gamma-aminobutyric acid type A receptors are activated. Reports indicate that acamprosate only works with a combination of attending support groups and abstinence from alcohol. Certain serious side effects include allergic reactions, irregular heartbeats, and low or high blood pressure, while less serious side effects include headaches, insomnia, and impotence. Acamprosate should not be taken by people with kidney problems or allergies to the drug.
Acamprosate mechanism of action
The mechanism of action of acamprosate in maintenance of alcohol abstinence is not completely understood. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition. iin vitro /i and iin vivo /i studies in animals have provided evidence to suggest acamprosate may interact with glutamate and GABA neurotransmitter systems centrally, and has led to the hypothesis that acamprosate restores this balance. It seems to inhibit NMDA receptors while activating GABA receptors.
Dosage forms of Acamprosate
|Campral||333mg||168 Enteric Coated Tablet||$98.00|
3-Acetamido-1-propanesulfonic acid Acamprosato
Mylan Institutional Inc.
Humans and other mammals
Indication of Acamprosate
For the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation
Toxicity of Acamprosate
In all reported cases of acute overdosage with acamprosate (total reported doses of up to 56 grams of acamprosate calcium), the only symptom that could be reasonably associated with acamprosate was diarrhea.
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