Save up -80% on Acetaminophen

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

Pharmacists and Patients support.

2018 Price of Acetaminophen

Tencon tablet



* price without discount in nearest pharmacy. Price may vary.

Claim your free Acetaminophen discount card

We offer free Acetaminophen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Acetaminophen every time. What are you waiting for? Claim your prescription drug card now!

Get your Prescription
It’s safe and free
Buy drugs in pharmacy
Save money each time

Acetaminophen volume of distribution

About RX24Drugs

Discount Cards 16,000+

Clients Benefit 29%

Total savings $4,735,080

What is Acetaminophen

Acetaminophen, also known as paracetamol, is commonly used for its analgesic and antipyretic effects. Its therapeutic effects are similar to salicylates, but it lacks anti-inflammatory, antiplatelet, and gastric ulcerative effects.

Acetaminophen mechanism of action

Acetaminophen is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Unlike NSAIDs, acetaminophen does not inhibit cyclooxygenase in peripheral tissues and, thus, has no peripheral anti-inflammatory affects. While aspirin acts as an irreversible inhibitor of COX and directly blocks the enzyme’s active site, studies have found that acetaminophen indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides. This might explain why acetaminophen is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. Studies also report data suggesting that acetaminophen selectively blocks a variant of the COX enzyme that is different from the known variants COX-1 and COX-2. This enzyme is now referred to as COX-3. Its exact mechanism of action is still poorly understood, but future research may provide further insight into how it works. The antipyretic properties of acetaminophen are likely due to direct effects on the heat-regulating centres of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.

Dosage forms of Acetaminophen

Tylenol Regular325mg100 Tablet$16.76
Tylenol Extra Strength500mg100 Tablet$18.61
Tylenol Infant DropsnoDose24mL Drops$14.90
Tylenol Arthritis Pain650mg100 Timed Release Caplets$22.49
Tylenol Childrens Suspension Grape80mg/5mL100mL Syrup (PMS)$14.41
Tylenol325mg96 Tablet (PMS)$34.20
Tylenol Ultra Relief Migrane500mg/65mg20 Tablet$13.20
Acetaminophen500mg100 Tablet$24.00
Robaxacet400/325mg40 Tablet$44.50
Robaxacet Extra Strength400/500mg72 Tablet$74.40
Methocarbamol/Acetaminophen400/500mg18 Caplet$34.00
Tempra Drops Banana80mg/mL24mL Drops (Banana)$15.30
Tempra Chewable Tablets80mg24 Chewable Tablet$12.30
Tempra Syrup Cherry160mg/5mL100mL Syrup (Cherry)$13.42
Prescription Generics


International Brands

(extra Strength) Acetaminophen, Caffeine 8mg Codeine Phosphate Caplets


4-(Acetylamino)phenol 4-acetamidophenol


Stanley Pharmaceuticals, A Division Of Vita Health Products Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Acetaminophen

For temporary relief of fever, minor aches, and pains.

Toxicity of Acetaminophen

Oral, mouse: LD50 = 338 mg/kg; Oral, rat: LD50 = 1944 mg/kg. Acetaminophen is metabolized primarily in the liver, where most of it is converted to inactive compounds by conjugation with glucuronic acid and, to a lesser extent, sulfuric acid. Conjugates are then excreted by the kidneys. Only a small portion is excreted in unchanged in urine or oxidized via the hepatic cytochrome P450 enzyme system (CYP2E1). Metabolism via CYP2E1 produces a toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). The toxic effects of acetaminophen are due to NAPQI, not acetaminophen itself nor any of the major metabolites. At therapeutic doses, NAPQI reacts with the sulfhydryl group of glutathione to produce a non-toxic conjugate that is excreted by the kidneys. High doses of acetaminophen may cause glutathione depletion, accumulation of NAPQI and hepatic necrosis. The maximum daily dose of acetaminophen is 4 g. Liver failure has been observed at doses as low as 6 g per day. As such, the maximum daily and single dose of acetaminophen is currently being reviewed in some countries. N-acetyl-cysteine, a precursor of glutathione, may be administered in the event of acetaminophen toxicity.

RX24 Drugs Disclaimer: before buying a Acetaminophen on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

Get lower price on Acetaminophen now!