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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Adapalene

Differin 0.1% cream



* price without discount in nearest pharmacy. Price may vary.

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Adapalene volume of distribution

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What is Adapalene

Adapalene is a topical retinoid primarily used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It is currently marketed by Galderma under the trade names Differin in some countries, and Adaferin in India. (Wikipedia)

Adapalene mechanism of action

Mechanistically, adapalene binds to specific retinoic acid nuclear receptors (gamma and beta) and retinoid X receptors but does not bind to the cytosolic receptor protein. Although the exact mode of action of adapalene is unknown, it is suggested that topical adapalene may normalize the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.

Dosage forms of Adapalene

Form Route Strength
Cream topical .1 g/100g
Cream topical 1 mg/g
Gel topical 45 g/g
Prescription Generics


International Brands



6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid Adaferin


Pru Gen, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Adapalene

For the topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.

Toxicity of Adapalene

The acute oral toxicity of adapalene in mice and rats is greater than 10 mL/kg. Chronic ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of Vitamin A.

RX24 Drugs Disclaimer: before buying a Adapalene on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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