Save up -80% on Alefacept
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Price of Alefacept
Amevive 15 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Alefacept volume of distribution
What is Alefacept
Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.
Alefacept mechanism of action
Inhibits T-lymphocyte activation and production by binding to the CD2 lymphocyte antigen.
Dosage forms of Alefacept
|Powder for solution||intramuscular||15 mg|
Astellas Pharma Canada Inc
Humans and other mammals
Indication of Alefacept
As an immunosuppressive drug, Alefacept can be used for treatment of moderate to severe chronic plaque psoriasis
Toxicity of Alefacept
While it has been found to cross the placenta in monkeys, it is not yet known if it also diffuses into breast milk.
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