Save up -80% on Alitretinoin
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Price of Alitretinoin
Retin-a 0.025% cream
* price without discount in nearest pharmacy. Price may vary.
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Alitretinoin volume of distribution
What is Alitretinoin
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute). (PubChem)
Alitretinoin mechanism of action
Alitretinoin binds to and activates all known intracellular retinoid receptor subtypes (RARa, RARb, RARg, RXRa, RXRb and RXRg). Once activated these receptors function as transcription factors that regulate the expression of genes that control the process of cellular differentiation and proliferation in both normal and neoplastic cells.
Dosage forms of Alitretinoin
|Gel||Cutaneous use||0.1 %|
Humans and other mammals
Indication of Alitretinoin
For topical treatment of cutaneous lesions in patients with AIDS-related Kaposi’s sarcoma.
Toxicity of Alitretinoin
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