Save up -80% on Alpha-Linolenic Acid

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Alpha-Linolenic Acid

Alpha-lipoic acid 50 mg caplet

$0.12

caplet

* price without discount in nearest pharmacy. Price may vary.

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Alpha-Linolenic Acid volume of distribution

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What is Alpha-Linolenic Acid

Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition. (Wikipedia)

Alpha-Linolenic Acid mechanism of action

Alpha Linolenic Acid or ALA is considered an essential fatty acid because it is required for human health, but cannot be synthesized by humans. It is in fact a plant-derived fatty acid. Humans can synthesize other omega-3 fatty acids from ALA, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). EPA is a precursor of the series-3 prostaglandins, the series-5 leukotrienes and the series-3 thromboxanes. These eicosanoids have anti-inflammatory and anti-atherogenic properties. ALA metabolites may also inhibit the production of the pro-inflammatory eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4 (LTB4), as well as the pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta). Omega-3 fatty acids like ALA and its byproducts can modulate the expression of a number of genes, including those involved with fatty acid metabolism and inflammation. They regulate gene expression through their effects on the activity of transcription factors including NF-kappa B and members of the peroxisome proliferator-activated receptor (PPAR) family. Incorporation of ALA and its metabolites in cell membranes can affect membrane fluidity and may play a role in anti-inflammatory activity, inhibition of platelet aggregation and possibly in anti-proliferative actions of ALA. ALA is first metabolized by delta6 desaturease into steridonic acid.

Dosage forms of Alpha-Linolenic Acid

FormRouteStrength
Capsule, gelatin coatedoral
Capsuleoral
Prescription Generics

false

International Brands

Folcaps Care One

Synonyms

(9,12,15)-linolenic acid (9Z,12Z,15Z)-Octadecatrienoic acid

Manufacturers

Midlothian Laboratories

CAS number

463-40-1

UNII

0RBV727H71

State

liquid

Affected organisms

Humans and other mammals

Indication of Alpha-Linolenic Acid

For nutritional supplementation and for treating dietary shortage or imbalance.

Toxicity of Alpha-Linolenic Acid

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