Save up -80% on Alprazolam
Note: this is a drug discount program, not an insurance plan.
2018 Price of Alprazolam
ALPRAZolam 0.5 mg 24 Hour tablet
* price without discount in nearest pharmacy. Price may vary.
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Alprazolam volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Alprazolam
A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of panic disorders, with or without agoraphobia, and in generalized anxiety disorders. (From AMA Drug Evaluations Annual, 1994, p238)
Alprazolam mechanism of action
Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABA subA /sub) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.
Dosage forms of Alprazolam
|Solution, concentrate||oral||1 mg/mL|
Humans and other mammals
Indication of Alprazolam
For the management of anxiety disorder or the short-term relief of symptoms of anxiety and for the treatment of panic disorder, with or without agoraphobia.
Toxicity of Alprazolam
Oral, mouse: LD sub50 /sub=1020 mg/kg. Symptoms of overdose include confusion, coma, impaired coordination, sleepiness, and slowed reaction time.
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