Save up -80% on Alteplase
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Price of Alteplase
Cathflo activase 2 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Alteplase volume of distribution
What is Alteplase
Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells
Alteplase mechanism of action
Alteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.
Dosage forms of Alteplase
|Liquid; powder for solution||intravenous|
|Powder for solution||intravenous||29 m|
Humans and other mammals
Indication of Alteplase
For management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli
Toxicity of Alteplase
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