Save up -80% on Alteplase
Note: this is a drug discount program, not an insurance plan.
2018 Price of Alteplase
Cathflo activase 2 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Alteplase volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Alteplase
Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells
Alteplase mechanism of action
Alteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.
Dosage forms of Alteplase
|Liquid; powder for solution||intravenous|
|Powder for solution||intravenous||29 m|
t-PA t-plasminogen activator
Humans and other mammals
Indication of Alteplase
For management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli
Toxicity of Alteplase
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