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Price of Amcinonide
Amcinonide 0.1% cream
* price without discount in nearest pharmacy. Price may vary.
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Amcinonide volume of distribution
What is Amcinonide
Amcinonide is a corticosteroid. (Wikipedia)
Amcinonide mechanism of action
The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Amcinonide has affinity for the glucocorticoid receptor. It has weak affinity for the progesterone receptor, and virtually no affinity for the mineralocorticoid, estrogen, or androgen receptors.
Dosage forms of Amcinonide
E. Fougera Co. a division of Fougera Pharmaceuticals Inc.
Humans and other mammals
Indication of Amcinonide
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Toxicity of Amcinonide
Results from acute toxicity studies do not indicate that any risk of acute intoxication is to be expected following a single dermal application of an overdose (application over a large area under conditions favorable to absorption) or inadvertent oral ingestion.
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