Save up -80% on Amifostine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Amifostine
|price without discount in nearest pharmacy. Price may vary.|
We offer free Amifostine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Amifostine every time. What are you waiting for? Claim your prescription drug card now!
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Amifostine volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Amifostine
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Amifostine mechanism of action
The thiol metabolite is responsible for most of the cytoprotective and radioprotective properties of amifostine. It is readily taken up by cells where it binds to and detoxifies reactive metabolites of platinum and alkylating agents as well as scavenges free radicals. Other possible effects include inhibition of apoptosis, alteration of gene expression and modification of enzyme activity.
Dosage forms of Amifostine
|Injection, powder, lyophilized, for solution||intravenous||50 mg/mL|
|Injection, powder, lyophilized, for solution||intravenous||500 mg/10mL|
|Powder for solution||intravenous||500 mg|
Sun Pharmaceutical Industries Limited
Humans and other mammals
Indication of Amifostine
For reduction in the cumulative renal toxicity in patients with ovarian cancer (using cisplatin) and moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer.
Toxicity of Amifostine
Rat LD sub50 /sub: 826 mg/kg
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