Save up -80% on Aminophylline
Note: this is a drug discount program, not an insurance plan.
2018 Price of Aminophylline
Aminophylline 200 mg tablet
* price without discount in nearest pharmacy. Price may vary.
We offer free Aminophylline coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Aminophylline every time. What are you waiting for? Claim your prescription drug card now!
Aminophylline volume of distribution
* 0.3 to 0.7 L/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Aminophylline
Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply.
Aminophylline mechanism of action
Aminophylline is the ethylenediamine salt of theophylline. After ingestion, theophylline is released from aminophylline, and theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction. In inflammatory states, theophylline activates histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones for transcription to begin.
Dosage forms of Aminophylline
|Injection, solution||intravenous||25 mg/mL|
West ward Pharmaceutical Corp
Humans and other mammals
Indication of Aminophylline
For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
Toxicity of Aminophylline
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