Save up -80% on Aminophylline

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Aminophylline

Aminophylline 200 mg tablet

$0.15

tablet

* price without discount in nearest pharmacy. Price may vary.

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Aminophylline volume of distribution

* 0.3 to 0.7 L/kg

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What is Aminophylline

Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply.

Aminophylline mechanism of action

Aminophylline is the ethylenediamine salt of theophylline. After ingestion, theophylline is released from aminophylline, and theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction. In inflammatory states, theophylline activates histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones for transcription to begin.

Dosage forms of Aminophylline

FormRouteStrength
Injection, solutionintravenous25 mg/mL
Tabletoral100 mg/1
Tabletoral200 mg/1
Prescription Generics

true

International Brands

Aminophylline

Synonyms

Aminophyllin Somophyllin

Manufacturers

West ward Pharmaceutical Corp

CAS number

317-34-0

UNII

27Y3KJK423

State

solid

Affected organisms

Humans and other mammals

Indication of Aminophylline

For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.

Toxicity of Aminophylline

RX24 Drugs Disclaimer: before buying a Aminophylline on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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