Save up -80% on Aminosalicylic Acid
Note: this is a drug discount program, not an insurance plan.
Price of Aminosalicylic Acid
Aminosalicylic acid powder
* price without discount in nearest pharmacy. Price may vary.
We offer free Aminosalicylic Acid coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your coupon in most local pharmacies to get a discount on Aminosalicylic Acid. Claim your prescription drug card now!
Aminosalicylic Acid volume of distribution
What is Aminosalicylic Acid
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid. (PubChem)
Aminosalicylic Acid mechanism of action
There are two mechanisms responsible for aminosalicylic acid’s bacteriostatic action against i Mycobacterium tuberculosis /i . Firstly, aminosalicylic acid inhibits folic acid synthesis (without potentiation with antifolic compounds). The binding of para-aminobenzoic acid to pteridine synthetase acts as the first step in folic acid synthesis. Aminosalicylic acid binds pteridine synthetase with greater affinity than para-aminobenzoic acid, effectively inhibiting the synthesis of folic acid. As bacteria are unable to use external sources of folic acid, cell growth and multiplication slows. Secondly, aminosalicylic acid may inhibit the synthesis of the cell wall component, mycobactin, thus reducing iron uptake by i M. tuberculosis /i .
Dosage forms of Aminosalicylic Acid
|Gastro-resistant v granules||Oral use||4 g|
|Granule, delayed release||oral||4 g/1|
Nemasol Sodium Tab 500mg
Icn Canada Ltd.
Indication of Aminosalicylic Acid
For the treatment of tuberculosis
Toxicity of Aminosalicylic Acid
LD sub 50 /sub =4 gm/kg (orally in mice); LD sub 50 /sub =3650 mg/kg (orally in rabbits)
Disclaimer: before buying a Aminosalicylic Acid on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.