Save up -80% on Amlexanox
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2018 Price of Amlexanox
Aphthasol 5% paste
* price without discount in nearest pharmacy. Price may vary.
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Amlexanox volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Amlexanox
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of the general population.
Amlexanox mechanism of action
As a benzopyrano-bipyridine carboxylic acid derivative, amlexanox has anti-inflammatory and antiallergic properties. It inhibits chemical mediatory release of the slow-reacting substance of anaphylaxis (SRS-A) and may have antagonistic effects on interleukin-3. When cells are under stress, they release an inactive form of human fibroblast growth factor 1 (FGF-1), a potent mitogen (entity that causes mitosis). Amlexanox binds to FGF1, increasing its conformational stability, sterically blocking Cu(2+) induced oxidation which normally leads to activation of FGF-1.
Dosage forms of Amlexanox
2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid Amlexanox
Humans and other mammals
Indication of Amlexanox
Used as a paste in the mouth to treat aphthous ulcers (canker sores).
Toxicity of Amlexanox
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