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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Adderall

$27.3460 tablets/20 mg
price without discount in nearest pharmacy. Price may vary.

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Amphetamine volume of distribution

Amphetamines are concentrated in the kidney, lungs, cerebrospinal fluid and brain. They are highly lipid soluble and readily cross the blood-brain barrier. Protein binding and volume of distribution varies widely, but the average volume of distribution is 5 L/kg body weight.

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2018 Statistics

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Discount Cards 16,000+


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Total savings $4,735,080

What is Amphetamine

Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. By mimicking the structures of the catecholamine neurotransmitters, noradrenaline and dopamine, amphetamines modulate monoamine release, reuptake, and signalling within the brain. Although “amphetamine” is used as a descriptor of its own structural class, amphetamine properly refers to a racemic free base composed of equal parts of its two optical antipodes: levo-amphetamine and dextro-amphetamine. Used in the past for the treatment of depression, stress, and for concentration improvement, it is currently available as a prescription drug for the treatment of attention hyperactivity disorder (ADHD), narcolepsy, and as an adjunct in the treatment of exogenous obesity. Amphetamine is also available in a mixed salt/mixed enantiomer form (Adderall), where d-amphetamine and l-amphetamine are available in a ratio of 3:1. It is also available in a prodrug form as lisdexamfetamine.

Amphetamine mechanism of action

Amphetamines stimulate the release of norepinephrine from central adrenergic receptors. At higher dosages, they cause release of dopamine from the mesocorticolimbic system and the nigrostriatal dopamine systems. Amphetamine may also act as a direct agonist on central 5-HT receptors and may inhibit monoamine oxidase (MAO). In the periphery, amphetamines are believed to cause the release of noradrenaline by acting on the adrenergic nerve terminals and alpha- and beta-receptors. Modulation of serotonergic pathways may contribute to the calming affect. The drug interacts with VMAT enzymes to enhance release of DA and 5-HT from vesicles. It may also directly cause the reversal of DAT and SERT.

Dosage forms of Amphetamine

Capsule (extended release)oral
Tablet, orally disintegratingoral12.5 mg/1
Tablet, orally disintegratingoral15.7 mg/1

Prescription Generics


International Brands

Act Amphetamine XR


1-phenyl-2-aminopropane 1-Phenylpropan-2-amin


Actavis Pharma Company

CAS number






Affected organisms

Humans and other mammals

Indication of Amphetamine

For treatment of Attention Deficit Disorder with Hyperactivity (ADDH), narcolepsy, and exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction for patients refractory to alternative therapy.

Toxicity of Amphetamine

LD sub 50 /sub =180 mg/kg(subcutaneous injection in rat). The most common presenting symptoms seen are agitation, hallucinations, suicidal behaviour, and chest pain.

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What is a Adderall?

Adderall contains a combination amphetamine and dextroamphetamine. Amphetamine and dextroamphetamine are central nervous system stimulants that affect chemicals in the brain and nerves that promote hyperactivity and impulse control. Adderall is used to treat narcolepsy and attention deficit hyperactivity disorder (ADHD). This medicine may also be used for purposes not listed in this guide.

You should not use Adderall if you have glaucoma, an overactive thyroid gland, severe arousal, moderate or severe high blood pressure, heart disease or coronary artery disease, or a history of drug addiction or alcohol dependence.

Do not use Adderall if you have taken an MAO inhibitor in the past 14 days, including isocarboxazid, linezolid, methylene blue injection, fenelzine, rasagiline, selegiline, tranylcypromine, and others.

Adderall may be familiar. Never share this medicine with another person, especially with drug or addiction. Using this medicine incorrectly can cause death or serious side effects on the heart.