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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Anastrozole

Aromasin 25 mg tablet

$14.04

tablet

* price without discount in nearest pharmacy. Price may vary.

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Anastrozole volume of distribution

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What is Anastrozole

Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer. It decreases the amount of estrogens that the body makes. Anastrozole belongs in the class of drugs known as aromatase inhibitors. It inhibits the enzyme aromatase, which is responsible for converting androgens (produced by women in the adrenal glands) to estrogens.

Anastrozole mechanism of action

Anastrozole selectively inhibits aromatase. The principal source of circulating estrogen (primarily estradiol) is conversion of adrenally-generated androstenedione to estrone by aromatase in peripheral tissues. Therefore, aromatase inhibition leads to a decrease in serum and tumor concentration of estrogen, leading to a decreased tumor mass or delayed progression of tumor growth in some women. Anastrozole has no detectable effect on synthesis of adrenal corticosteroids, aldosterone, and thyroid hormone.

Dosage forms of Anastrozole

DrugDosageQuantityPrice
Arimidex1mg28 Tablet$42.95
Arimidex1mg84 Tablet$104.95
Anastrozole1mg28 Film Coated Tablet$39.00
Anastrozole1mg84 Film Coated Tablet$97.00
Prescription Generics

false

International Brands

Accel-anastrozole Tablets

Synonyms

alpha,alpha,Alpha’,alpha’-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile Anastrozol

Manufacturers

Accel Pharma Inc

CAS number

120511-73-1

UNII

2Z07MYW1AZ

State

solid

Affected organisms

Humans and other mammals

Indication of Anastrozole

For adjuvant treatment of hormone receptor positive breast cancer , as well as hormonal treatment of advanced breast cancer in post-menopausal women. Has also been used to treat pubertal gynecomastia and McCune-Albright syndrome; however, manufacturer states that efficacy for these indications have not been established.

Toxicity of Anastrozole

In rats, lethality is greater than 100 mg/kg.

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