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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Eraxis

$96.501 vial/50mg
Price with discount in nearest pharmacy. Price may vary.

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Anidulafungin volume of distribution

The pharmacokinetics of anidulafungin are characterised by a rapid distribution half-life (0.5-1 hour) and a volume of distribution, 30-50 l, which is similar to total body fluid volume. Anidulafungin is extensively bound (> 99%) to human plasma proteins.

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What is Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin. (Wikipedia)

Anidulafungin mechanism of action

Anidulafungin is a semi-synthetic echinocandin with antifungal activity. Anidulafungin inhibits glucan synthase, an enzyme present in fungal, but not mammalian cells. This results in inhibition of the formation of 1,3- beta;-D-glucan, an essential component of the fungal cell wall, ultimately leading to osmotic instability and cell death.

Dosage forms of Anidulafungin

Injection, powder, lyophilized, for solutionintravenous100 mg/30mL
Injection, powder, lyophilized, for solutionintravenous50 mg/15mL
Powder for solutionintravenous100 mg

Prescription Generics


International Brands



(4R,5R)-4,5-Dihydroxy-N-((4”-(pentyloxy)-p-terphenyl-4-yl)carbonyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4(p-hydroxyphenyl)-L-threonyl-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-proline cyclic (6- 1)-peptide Anidulafungin


Pfizer Canada Inc

CAS number






Affected organisms

Candida albicans and other yeasts

Indication of Anidulafungin

For use in the treatment of the following fungal infections: Candidemia and other forms of i Candida /i infections (intra-abdominal abscess, and peritonitis), Aspergillus infections, and esophageal candidiasis. Also considered an alternative treatment for oropharyngeal canaidiasis.

Toxicity of Anidulafungin

During clinical trials a single 400 mg dose of anidulafungin was inadvertently administered as a loading dose. No clinical adverse events were reported. The maximum non-lethal dose of anidulafungin in rats was 50 mg/kg, a dose which is equivalent to 10 times the recommended daily dose for esophageal candidiasis (50mg/day).

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