Save up -80% on Apraclonidine

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Apraclonidine

Iopidine 0.5 % Solution

$4.79

ml

* price without discount in nearest pharmacy. Price may vary.

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Apraclonidine volume of distribution

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What is Apraclonidine

Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.

Apraclonidine mechanism of action

Apraclonidine is a relatively selective alpha2 adrenergic receptor agonist that stimulates alpha1 receptors to a lesser extent. It has a peak ocular hypotensive effect occurring at two hours post-dosing. The exact mechanism of action is unknown, but fluorophotometric studies in animals and humans suggest that Apraclonidine has a dual mechanism of action by reducing aqueous humor production through the constriction of afferent ciliary process vessels, and increasing uveoscleral outflow.

Dosage forms of Apraclonidine

DrugDosageQuantityPrice
Iopidine Eyedrops0.50%5mL Drops$55.00
Prescription Generics

false

International Brands

Apraclonidine

Synonyms

4-Aminoclonidine Apraclonidina

Manufacturers

Sandoz Inc.

CAS number

66711-21-5

UNII

843CEN85DI

State

solid

Affected organisms

Humans and other mammals

Indication of Apraclonidine

For prevention or reduction of intraoperative and postoperative increases in intraocular pressure (IOP) before and after ocular laser surgery when used prophylactically. Also used as a short-term adjunctive therapy in patients with open-angle glaucoma who are on maximally tolerated medical therapy requiring additional IOP reduction.

Toxicity of Apraclonidine

Accidental or intentional ingestion of oral apraclonidine has been reported to cause apnea, arrhythmias, asthenia, bradycardia, conduction defects, diminished or absent reflexes, dryness of the mouth, hypotension, hypothermia, hypoventilation, irritability, lethargy, miosis, pallor, respiratory depression, sedation or coma, seizure, somnolence, transient hypertension, and vomiting.

RX24 Drugs Disclaimer: before buying a Apraclonidine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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