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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Armodafinil

$

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Armodafinil volume of distribution

Apparent volume of distribution: 42L.

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What is Armodafinil

Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the ( )-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.

Armodafinil mechanism of action

Nuvigil (armodafinil) is a single-isomer of modafini. The exact mechanism of action is unknown. Armodafinil belongs to a class of drugs known as eugeroics, which are stimulants that provide long-lasting mental arousal. Pharmacologically, armodafinil does not bind to or inhibit several receptors and enzymes potentially relevant for sleep/wake regulation. Armodafinil is not a direct- or indirect-acting dopamine receptor agonist. However, in vitro, both armodafinil and modafinil bind to the dopamine transporter and inhibit dopamine reuptake.[Medilexicon]

Dosage forms of Armodafinil

FormRouteStrength
Tabletoral100 mg/1
Tabletoral200 mg/1
Tabletoral150 mg/1
Prescription Generics

true

International Brands

Armodafinil

Synonyms

( -2-[(R)-(diphenylmethyl)sulfinyl]acetamide R-modafinil

Manufacturers

Watson Laboratories, Inc.

CAS number

112111-43-0

UNII

V63XWA605I

State

solid

Affected organisms

Humans and other mammals

Indication of Armodafinil

Investigated for use/treatment in sleep disorders, obstructive sleep apnea, schizophrenia and schizoaffective disorders, depression, and bipolar disorders.

Toxicity of Armodafinil

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