Save up -80% on Arsenic trioxide
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Arsenic Trisenox
|price without discount in nearest pharmacy. Price may vary.|
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Arsenic trioxide volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Arsenic trioxide
Arsenic trioxide is a chemotheraputic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. Due to the toxic nature of arsenic, this drug carries significant health risks. The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Arsenic trioxide mechanism of action
The mechanism of action of Arsenic Trioxide is not completely understood. Arsenic trioxide causes morphological changes and DNA fragmentation characteristic of apoptosis in NB4 human promyelocytic leukemia cells iin vitro /i. Arsenic trioxide also causes damage or degradation of the fusion protein PML/RAR-alpha. It is suspected that arsenic trioxide induces cancer cells to undergo apoptosis.
Dosage forms of Arsenic trioxide
|Injection, solution||intravenous||1 mg/mL|
Acide Arsenieux Anhydride Arsenieux
Humans and other mammals
Indication of Arsenic trioxide
For induction of remission and consolidation in patients with acute promyelocytic leukemia (APL), and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression
Toxicity of Arsenic trioxide
Symptoms of overdose include convulsions, muscle weakness and confusion.
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