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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Arsenic Trisenox

$2.59g
price without discount in nearest pharmacy. Price may vary.

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Arsenic trioxide volume of distribution

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2018 Statistics

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What is Arsenic trioxide

Arsenic trioxide is a chemotheraputic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. Due to the toxic nature of arsenic, this drug carries significant health risks. The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.

Arsenic trioxide mechanism of action

The mechanism of action of Arsenic Trioxide is not completely understood. Arsenic trioxide causes morphological changes and DNA fragmentation characteristic of apoptosis in NB4 human promyelocytic leukemia cells iin vitro /i. Arsenic trioxide also causes damage or degradation of the fusion protein PML/RAR-alpha. It is suspected that arsenic trioxide induces cancer cells to undergo apoptosis.

Dosage forms of Arsenic trioxide

FormRouteStrength
Injection, solutionintravenous1 mg/mL
Solutionintravenous1 mg

Prescription Generics

false

International Brands

Trisenox

Synonyms

Acide Arsenieux Anhydride Arsenieux

Manufacturers

Cephalon, Inc.

CAS number

1327-53-3

UNII

S7V92P67HO

State

solid

Affected organisms

Humans and other mammals

Indication of Arsenic trioxide

For induction of remission and consolidation in patients with acute promyelocytic leukemia (APL), and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression

Toxicity of Arsenic trioxide

Symptoms of overdose include convulsions, muscle weakness and confusion.

RX24 Drugs Disclaimer: before buying a Arsenic trioxide on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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