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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Auranofin

Ridaura 3 mg capsule

$5.17

capsule

* price without discount in nearest pharmacy. Price may vary.

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Auranofin volume of distribution

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What is Auranofin

Auranofin is a organogold compound classified by the World Health Organization as an antirheumatic agent. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is an inducible heme-degrading enzyme with anti-inflammatory properties.

Auranofin mechanism of action

Exactly how auranofin works is not well understood. It may act as an inhibitor of kappab kinase and thioredoxin reductase which would lead to a decreased immune response and decreased free radical production, respectively. In patients with inflammatory arthritis, such as adult and juvenile rheumatoid arthritis, gold salts can decrease the inflammation of the joint lining. This effect can prevent destruction of bone and cartilage.

Dosage forms of Auranofin

DrugDosageQuantityPrice
Ridaura3mg60 Capsule$425.00
Prescription Generics

false

International Brands

Ridaura

Synonyms

(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold

Manufacturers

Prometheus Laboratories Inc.

CAS number

34031-32-8

UNII

3H04W2810V

State

solid

Affected organisms

Humans and other mammals

Indication of Auranofin

Used in the treatment of active, progressive or destructive forms of inflammatory arthritis, such as adult rheumatoid arthritis.

Toxicity of Auranofin

Oral, rat: LD sub 50 /sub = 2000 mg/kg. Symptoms of overdose may include diarrhoea, vomiting, abdominal cramps, and symptoms of hypersensitivity (such as skin rash, hives, itching, and difficulty breathing).

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