Save up -80% on Azathioprine

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Azathioprine

Imuran 50 mg Tablet

$2.76

tablet

* price without discount in nearest pharmacy. Price may vary.

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Azathioprine volume of distribution

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What is Azathioprine

An immunosuppressive antimetabolite pro-drug. It is an imidazolyl derivative of 6-mercaptopurine and many of its biological effects are similar to those of the parent compound. Azathioprine is converted into 6-mercaptopurine in the body where it blocks purine metabolism and DNA synthesis.

Azathioprine mechanism of action

Azathioprine antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins. It may also interfere with cellular metabolism and inhibit mitosis. Its mechanism of action is likely due to incorporation of thiopurine analogues into the DNA structure, causing chain termination and cytotoxicity.

Dosage forms of Azathioprine

DrugDosageQuantityPrice
Imuran25mg100 Tablet$47.90
Imuran50mg100 Tablet$54.70
Azathioprine25mg100 Tablet$38.30
Azathioprine50mg100 Tablet$83.00
Prescription Generics

true

International Brands

Apo-azathioprine

Synonyms

6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine 6-(1′-Methyl-4′-nitro-5′-imidazolyl)-mercaptopurine

Manufacturers

Apotex Inc

CAS number

446-86-6

UNII

MRK240IY2L

State

solid

Affected organisms

Humans and other mammals

Indication of Azathioprine

For use in rheumatoid arthritis, preventing renal transplant rejection, Crohn’s disease, and colitis.

Toxicity of Azathioprine

The oral LD sub 50 /sub for single doses of azathioprine in mice and rats are 2500 mg/kg and 400 mg/kg, respectively. Very large doses of this antimetabolite may lead to marrow hypoplasia, bleeding, infection, and death.

RX24 Drugs Disclaimer: before buying a Azathioprine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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