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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Imuran

$23.8360 tablets/50mg
price without discount in nearest pharmacy. Price may vary.

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Azathioprine volume of distribution

The volume of distribution were 41.6 +/- 12.1 min, 48.4 +/- 15.4 ml/min/kg, and 1.76 +/- 0.64 liters/kg, respectively. 8-Hydroxymercpatopurine (8-OHMP) was identified as a metabolites of AZA. 8-OHMP had a CLp twice that for 6-MP, while its Vdss was similar to that for 6-MP. After an iv dose, AZA is converted to 6-MP to the extent of 15%.

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What is Azathioprine

An immunosuppressive antimetabolite pro-drug. It is an imidazolyl derivative of 6-mercaptopurine and many of its biological effects are similar to those of the parent compound. Azathioprine is converted into 6-mercaptopurine in the body where it blocks purine metabolism and DNA synthesis.

Azathioprine mechanism of action

Azathioprine antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins. It may also interfere with cellular metabolism and inhibit mitosis. Its mechanism of action is likely due to incorporation of thiopurine analogues into the DNA structure, causing chain termination and cytotoxicity.

Dosage forms of Azathioprine

Imuran25mg100 Tablet$47.90
Imuran50mg100 Tablet$54.70
Azathioprine25mg100 Tablet$38.30
Azathioprine50mg100 Tablet$83.00

Prescription Generics


International Brands



6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine 6-(1′-Methyl-4′-nitro-5′-imidazolyl)-mercaptopurine


Apotex Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Azathioprine

For use in rheumatoid arthritis, preventing renal transplant rejection, Crohn’s disease, and colitis.

Toxicity of Azathioprine

The oral LD sub 50 /sub for single doses of azathioprine in mice and rats are 2500 mg/kg and 400 mg/kg, respectively. Very large doses of this antimetabolite may lead to marrow hypoplasia, bleeding, infection, and death.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Azathioprine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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