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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Dymista

$194.611 nasal spray (23g) 136 mcg
Price with discount in nearest pharmacy. Price may vary.

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Azelastine volume of distribution

Distribution. Based on intravenous and oral administration, the steady-state volume of distribution of azelastine is 14.5 L/kg. In vitro studies with human plasma indicate that the plasma protein binding of azelastine and its metabolite, desmethylazelastine, are approximately 88% and 97%, respectively.

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2018 Statistics

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Total savings $4,735,080

What is Azelastine

Azelastine, a phthalazine derivative, is an antihistamine and mast cell stabilizer available as a nasal spray for hay fever and as eye drops for allergic conjunctivitis. Azelastine is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymista. Dymista is indicated in patient over 12 years old for symptomatic relief of seasonal allergic rhinitis.

Azelastine mechanism of action

Azelastine competes with histamine for the H1-receptor sites on effector cells and acts as an antagonist by inhibiting the release of histamine and other mediators involved in the allergic response.

Dosage forms of Azelastine

Rhinolast Nasal Spray137mcg22mL Nasal spray$45.00
Azelastine0.1%10mL Nasal Spray$33.00
Azelastine0.1%20mL Nasal Spray$57.00
Astelin Nasal Spray137mcg22mL Nasal Spray$45.00
Astelin Nasal Spray137mcg66mL Nasal Spray$98.00
Optivar0.05%16mL Eye Drops$72.00
Astepro Nasal Spray0.15%30mL Nasal spray$235.00
Dymista137/50mcg120doses Nasal Spray$138.00

Prescription Generics


International Brands



4-(P-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone Azelastina


Physicians Total Care, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Azelastine

For the symptomatic treatment of seasonal allergic rhinitis and non-allergic rhinitis, as well as symptomatic relief of ocular itching associated with allergic conjunctivitis.

Toxicity of Azelastine

Overdose data is limited. Since each bottle of a nasal spray contains 30 mg of azelastine hydrochloride, acute overdose in adults is unlikely to result in clinically significant adverse events, other than increased somnolence. In studies, adults did not experience increased incidence of serious adverse events following single doses of the oral formulation of azelastine hydrochloride (up to 16 mg).

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Azelastine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is Astero?

Astero is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can cause symptoms of sneezing, itching, watery eyes and runny nose.

Astepro Nasal Spray prevents sneezing, itching, runny nose and other nasal allergy symptoms. This medicine is intended for seasonal allergies in adults and children who are at least 2 years old, and for year-round allergies in adults and children 6 months of age.

Astepro Nasal Spray can damage your thinking or reactions. Be careful if you are driving or doing everything that requires your attention. Before using Astepro, tell your doctor if you regularly use other medicines that make you sleep (for example, cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for cramps, depression or anxiety). They can add to sleepiness caused by Astepro.

What is a Dymista?

Dymista Nasal Spray contains a combination of azelastine and fluticasone. Azelastine is an antihistamine that reduces the effect of natural chemical histamine in the body. Histamine can cause symptoms of sneezing, itching, watery eyes and a runny nose.

Dymista Nasal Spray is used to treat nasal symptoms such as congestion, sneezing and runny nose, caused by seasonal allergies. Dymista nasal spray is intended for adults and children who are at least 6 years old.

Before you use Dymista, tell your doctor if you have glaucoma or cataracts, diabetes, herpes simplex virus, tuberculosis, or any other infection, ulcers or sores inside your nose, or if you have recently had a trauma or nose surgery.

It can take up to several days of using Dymista nasal spray before your symptoms improve. Tell your doctor if your symptoms do not improve after a week of treatment.

Do not share Dymista with other people, even if they have the same symptoms that you have. Do not give this medicine to a child under the age of 12 without medical advice. Steroid drugs can affect growth in children. Talk to your doctor if you think your child does not grow at a normal rate when using this medication.