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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Baclofen

Lioresal D.S. 20 mg Tablet



* price without discount in nearest pharmacy. Price may vary.

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Baclofen volume of distribution

* 59 L

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What is Baclofen

Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant. Baclofen stimulates GABA-B receptors leading to decreased frequency and amplitude of muscle spasms. It is especially useful in treating muscle spasticity associated with spinal cord injury. It appears to act primarily at the spinal cord level by inhibiting spinal polysynaptic afferent pathways and, to a lesser extent, monosynaptic afferent pathways.

Baclofen mechanism of action

Baclofen is a direct agonist at GABAB receptors. The precise mechanism of action of Baclofen is not fully known. It is capable of inhibiting both monosynaptic and polysynaptic reflexes at the spinal level, possibly by hyperpolarization of afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical effect.

Dosage forms of Baclofen

Form Route Strength
Injection intrathecal 10 mg/20mL
Injection intrathecal 40 mg/20mL
Tablet oral 10 mg/1
Prescription Generics


International Brands

Apo-baclofen Tablets – 10mg


(+-)-Baclofen 4-Amino-3-(4-chlorophenyl)butyric acid


Apotex Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Baclofen

For the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.

Toxicity of Baclofen

LD sub 50 /sub =45 mg/kg (male mice, IV); LD sub 50 /sub =78 mg/kg (male rat, IV)

RX24 Drugs Disclaimer: before buying a Baclofen on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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