Save up -80% on Baclofen
Note: this is a drug discount program, not an insurance plan.
2018 Price of Baclofen
Lioresal D.S. 20 mg Tablet
* price without discount in nearest pharmacy. Price may vary.
We offer free Baclofen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Baclofen every time. What are you waiting for? Claim your prescription drug card now!
Baclofen volume of distribution
* 59 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Baclofen
Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant. Baclofen stimulates GABA-B receptors leading to decreased frequency and amplitude of muscle spasms. It is especially useful in treating muscle spasticity associated with spinal cord injury. It appears to act primarily at the spinal cord level by inhibiting spinal polysynaptic afferent pathways and, to a lesser extent, monosynaptic afferent pathways.
Baclofen mechanism of action
Baclofen is a direct agonist at GABAB receptors. The precise mechanism of action of Baclofen is not fully known. It is capable of inhibiting both monosynaptic and polysynaptic reflexes at the spinal level, possibly by hyperpolarization of afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical effect.
Dosage forms of Baclofen
Apo-baclofen Tablets – 10mg
(+-)-Baclofen 4-Amino-3-(4-chlorophenyl)butyric acid
Humans and other mammals
Indication of Baclofen
For the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.
Toxicity of Baclofen
LD sub 50 /sub =45 mg/kg (male mice, IV); LD sub 50 /sub =78 mg/kg (male rat, IV)
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