Save up -80% on Basiliximab

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Basiliximab

Simulect 10 mg vial

$1883.11

vial

* price without discount in nearest pharmacy. Price may vary.

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Basiliximab volume of distribution

* 7.8 . 5.1 L[Pediatric]; * 4.8 . 2.1 L[Adult]

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What is Basiliximab

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.

Basiliximab mechanism of action

Basiliximab binds with high-affinity to the alpha-subunit (CD25) of the high-affinity IL-2 receptor. This inhibits IL-2 binding, which inhibits T-cell activation and prevents the body from mounting an immune response against the foreign kidney.

Dosage forms of Basiliximab

FormRouteStrength
Injection, powder, for solutionintravenous10 mg/2.5mL
Injection, powder, for solutionintravenous20 mg/5mL
Powder and solvent for solution for injection or infusionIntravenous use20 mg
Prescription Generics

false

International Brands

Simulect

Synonyms

chimeric mouse-human antiCD25 Ig gamma-1 chain C region

Manufacturers

Novartis Pharmaceuticals Canada Inc

CAS number

179045-86-4

UNII

9927MT646M

State

liquid

Affected organisms

Humans and other mammals

Indication of Basiliximab

For prophylactic treatment of kidney transplant rejection

Toxicity of Basiliximab

RX24 Drugs Disclaimer: before buying a Basiliximab on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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