Save up -80% on Becaplermin
Note: this is a drug discount program, not an insurance plan.
2018 Price of Becaplermin
Regranex 0.01% gel
* price without discount in nearest pharmacy. Price may vary.
We offer free Becaplermin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Becaplermin every time. What are you waiting for? Claim your prescription drug card now!
Becaplermin volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Becaplermin
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds.
Becaplermin mechanism of action
Binds to the beta platelet-derived growth factor (PDGF) receptor, a tyrosine kinase receptor. PDGF is known to exist as a dimer, and activates its signaling pathway by a ligand induced receptor dimerization and autophosphorylation. PDGF receptors also contain many auto-phosphorylation sites, which serve to mediate binding of SH2 sites and subsequently signal corresponding pathways. There are five different isoforms of PDGF that activate through two different receptors (alpha and beta).
Dosage forms of Becaplermin
|Gel||Cutaneous use||0.01 %|
c-sis PDGF B-chain
Humans and other mammals
Toxicity of Becaplermin
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