Save up -80% on Becaplermin

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Regranex

$1,115.961 tube (15g) 0.01% gel
price without discount in nearest pharmacy. Price may vary.

Claim your free Becaplermin discount card

We offer free Regranex coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Becaplermin every time. What are you waiting for? Claim your prescription drug card now!

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Becaplermin volume of distribution

Diabetic patients develop a stereotypical pattern of lower extremity atherosclerotic lesions in a more peripheral distribution when compared to non-diabetic patients. However, even limbs free from overt arterial insufficiency may suffer from a number of abnormalities in the micro-circulation that contribute to local tissue hypoxia.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Becaplermin

Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds.

Becaplermin mechanism of action

Binds to the beta platelet-derived growth factor (PDGF) receptor, a tyrosine kinase receptor. PDGF is known to exist as a dimer, and activates its signaling pathway by a ligand induced receptor dimerization and autophosphorylation. PDGF receptors also contain many auto-phosphorylation sites, which serve to mediate binding of SH2 sites and subsequently signal corresponding pathways. There are five different isoforms of PDGF that activate through two different receptors (alpha and beta).

Dosage forms of Becaplermin

FormRouteStrength
GelCutaneous use0.01 %
Geltopical100 ug/g
Geltopical100 mcg

Prescription Generics

false

International Brands

Regranex

Synonyms

c-sis PDGF B-chain

Manufacturers

HEALTHPOINT, LTD

CAS number

165101-51-9

UNII

1B56C968OA

State

liquid

Affected organisms

Humans and other mammals

Indication of Becaplermin

For topical treatment of skin ulcers (from diabetes)

Toxicity of Becaplermin

No significant local or systemic toxicity directly attributable to becaplermin was observed following single and multiple intravenous or subcutaneous administration at doses up to 3 mg/kg in monkeys. Administration of single large intravenous doses (up to 100 mg/kg) and repeated dosing at 1 or 3 mg/kg in mice resulted in rapidly reversible vasodilation and central nervous system depression.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Becaplermin on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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