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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Qvar

$210.121 redihaler (10.6g) 80mcg
price without discount in nearest pharmacy. Price may vary.

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Beclomethasone dipropionate volume of distribution

The steady state volume of distribution for beclomethasone dipropionate is 20 L, and for it’s active metabolite, beclomethasone-17-monopropionate, it is much larger at 424 L.

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What is Beclomethasone dipropionate

Beclomethasone dipropionate is a prodrug of the free form, Beclomethasone (beclomethasone-17-monopropionate). An anti-inflammatory, synthetic corticosteroid, it is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma and allergic rhinitis (seasonal and perennial). Beclometasone dipropionate is also being investigated for oral treatment in mild-to-moderate Crohn’s disease of ileal or ileal-right colonic localisation and for “topical” use mild-to-moderate graft versus host disease. It is marketed under several brand names such as Qnasl (US) and Rivanase AQ (Canada).

Beclomethasone dipropionate mechanism of action

Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. For the investigated use in the treatment of GvHD or Crohn’s, beclometasone acts by binding to interleukin-13 to inhibit cytokines, which in turn inhibits inflammatory chemicals downstream.

Dosage forms of Beclomethasone dipropionate

DrugDosageQuantityPrice
Beclomethasone Dipropionate50mcg600doses Nasal Spray$52.50
Qnasl Nasal Aerosol80mcg120doses Nasal Spray$222.00
Beconase Aq Nasal50mcg600ds Nasal Spray$76.00
Quadriderm Cream0.025/1/0.5/0.1%5g Cream$17.40
Quadriderm Cream0.025/1/0.5/0.1%10g Cream$26.50

Prescription Generics

false

International Brands

Alti-beclomethasone Dipropionate Inhaler 50mcg/md

Synonyms

(11beta,16beta)-9-chloro-11-Hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione 9-chloro-11beta-Hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

Manufacturers

Altimed Pharma Inc.

CAS number

5534-09-8

UNII

5B307S63B2

State

solid

Affected organisms

Humans and other mammals

Indication of Beclomethasone dipropionate

Used in the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older, and in treating symptoms for allergic rhinitis (seasonal or perennial) in patients 12 years of age and older. Also being investigated for oral treatment in mild-to-moderate Crohn’s disease of ileal or ileal-right colonic localisation and for “topical” use mild-to-moderate graft versus host disease.

Toxicity of Beclomethasone dipropionate

The acute toxicity of beclometasone dipropionate is low. The only harmful effect that follows inhalation of large amounts of the drug over a short period of time is suppression of hypothalamic-pituitary-adrenal (HPA) function. Chronic: The excessive use of beclometasone dipropionate over a long period could lead to adrenal suppression.

RX24 Drugs Disclaimer: before buying a Beclomethasone dipropionate on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is Qvar?

Qvar Autohaler contains beclomethasone dipropionate anti-inflammatory drugs. This substance belongs to the group of glucocorticosteroids. The patient inhales the drug, suffers from chronic inflammation of the airways.

Qvar Autohaler is used for basic therapy of bronchial asthma in adults and children over 5 years. The effect occurs only after a few days, and it depends on the consistent application and the correct dosage (dosage and number of daily single doses, regular use). With acute exacerbation of asthma, the drug has no effect.

This medicine should be used only as directed by the physician.

What is Qnasl?

Qnasl contains beclomethasone, a corticosteroid. This prevents the release of substances in the body that cause inflammation. Qnasl Nasal Spray (80 µg) is a prescription drug that treats seasonal nasal and round nasal allergy symptoms in adults and children 12 years of age and older.

Before using Qnasl Nasal Aerosol, tell your doctor if you are sick or have had any infection. Also tell your doctor if you have glaucoma or cataract, herpes simplex infection of your eyes, tuberculosis, ulcers or ulcers in the nose, or if you have recently had an injury or nose surgery.

It may take up to 2 weeks before your symptoms improve. Continue using Qnasl Nasal Aerosol as directed and tell your doctor if your symptoms do not improve after 1 week of treatment.

To prevent this medicine from causing harmful effects on your nose or sinuses, your doctor may regularly check your progress. Do not miss the scheduled visits to the doctor.

Beclomethasone can reduce blood cells that help your body fight infections. Avoid being near sick people or having infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal for people who use Qnasl. Avoid getting this medicine in your eyes. If this happens, rinse with water and call your doctor.

Steroid drugs can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate when using Qnasl.