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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Sirturo

$3,811

100mg

* price without discount in nearest pharmacy. Price may vary.

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Bedaquiline volume of distribution

Vd, central compartment = 164 L

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What is Bedaquiline

Bedaquiline is a bactericidal antimycobacterial drug. Chemically it is a diarylquinoline. FDA approved on December 28, 2012.

Bedaquiline mechanism of action

Bedaquiline is a diarylquinoline antimycobacterial drug that inhibits the proton pump of mycobacterial ATP (adenosine 5′-triphosphate) synthase, an enzyme that is essential for the generation of energy in Mycobacterium tuberculosis. Bacterial death occurs as a result of bedaquiline.

Dosage forms of Bedaquiline

DrugDosageQuantityPrice
Sirturo100mg24 tabletes$3,915
Prescription Generics

false

International Brands

Sirturo

Synonyms

1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol Bedaquilina

Manufacturers

Janssen Products, LP

CAS number

843663-66-1

UNII

78846I289Y

State

solid

Affected organisms

Mycobacterium tuberculosis

Indication of Bedaquiline

Bedaquiline is indicated as part of combination therapy in adults ( 18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB).

Toxicity of Bedaquiline

The most common adverse reactions reported in 10% of patients treated with bedaquiline are nausea, arthralgia, and headache.

RX24 Drugs Disclaimer: before buying a Bedaquiline on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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