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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Sirturo



* price without discount in nearest pharmacy. Price may vary.

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Bedaquiline volume of distribution

Vd, central compartment = 164 L

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What is Bedaquiline

Bedaquiline is a bactericidal antimycobacterial drug. Chemically it is a diarylquinoline. FDA approved on December 28, 2012.

Bedaquiline mechanism of action

Bedaquiline is a diarylquinoline antimycobacterial drug that inhibits the proton pump of mycobacterial ATP (adenosine 5′-triphosphate) synthase, an enzyme that is essential for the generation of energy in Mycobacterium tuberculosis. Bacterial death occurs as a result of bedaquiline.

Dosage forms of Bedaquiline

Sirturo100mg24 tabletes$3,915
Prescription Generics


International Brands



1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol Bedaquilina


Janssen Products, LP

CAS number






Affected organisms

Mycobacterium tuberculosis

Indication of Bedaquiline

Bedaquiline is indicated as part of combination therapy in adults ( 18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB).

Toxicity of Bedaquiline

The most common adverse reactions reported in 10% of patients treated with bedaquiline are nausea, arthralgia, and headache.

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