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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Benzonatate

Tessalon perle 100 mg capsule

$1.4

capsule

* price without discount in nearest pharmacy. Price may vary.

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What is Benzonatate

Benzonatate is a non-narcotic oral antitussive (cough suppressant) drug which works by anesthetizing the tissues of the lungs and pleura responsible for the cough reflex. It is chemically related to other ester anesthetics such as procaine. It has an anesthetic (numbing) action similar to that of benzocaine and “numbs” the stretch sensors in the lungs. It is the stretching of these sensors with breathing that causes the cough. It was approved by the FDA in 1958.

Benzonatate mechanism of action

Benzonatate acts peripherally, anesthetizing the stretch receptors of vagal afferent fibers in the alveoli of the lungs, bronchi, and pleura. Since these receptors are responsible for mediating the cough reflex, anesthetizing these receptors result in the inhibiton of cough production. Benzonatate also suppresses transmission of the cough reflex at the level of the medulla where the afferent impulse is transmitted to the motor nerves. When applied locally, Benzonatate binds within the intracellular portion of voltage-gated sodium channels, decreasing the rate of membrane depolarization and increasing the threshold for electrical excitability.

Dosage forms of Benzonatate

DrugDosageQuantityPrice
Benzonatate100mg90 Capsule$52.00
Benzonatate200mg90 Soft Gel$90.00
Prescription Generics

true

International Brands

Benzonatate

Synonyms

2-(2-(2-(2-(2-(2-(2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl 4-butylaminobenzoate 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl P-(butylamino)benzoate

Manufacturers

Amneal Pharmaceuticals of NY LLC

CAS number

104-31-4

UNII

5P4DHS6ENR

State

liquid

Affected organisms

Humans and other mammals

Indication of Benzonatate

For the symptomatic relief of cough. Has also been applied locally in the oral cavity in adults by releasing the drug from the liquid-filled capsules to provide oropharyngeal anesthesia for conscious intubation.

Toxicity of Benzonatate

Restlessness, tremors, seizures and unconsciousness.

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