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Price of Bexarotene
Targretin 1% gel
* price without discount in nearest pharmacy. Price may vary.
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Bexarotene volume of distribution
What is Bexarotene
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi’s sarcoma. (Wikipedia)
Bexarotene mechanism of action
Bexarotene selectively binds with and activates retinoid X receptor subtypes. There are three subtypes in total: RXR sub /sub , RXR sub /sub , RXR sub /sub . The exact mechanism of action of bexarotene in the treatment of CTCL is unknown but the drug has activity in all clinical stages of CTCL.
Dosage forms of Bexarotene
|Capsule, liquid filled||oral||75 mg/1|
|Capsule, soft||Oral use||75 mg|
Mylan Institutional Inc.
Humans and other mammals
Indication of Bexarotene
Used orally for the treatment of skin manifestations of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to at least one prior systemic therapy. Also used topically for the treatment of skin lesions in early (stage IA and IB) CTCL in patients who experience refractory or persistent disease with the use of other therapies or are intolerant of other therapies.
Toxicity of Bexarotene
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