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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Lumigan

$61.011 bottle (5ml) 0.03% solution
price without discount in nearest pharmacy. Price may vary.

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Bimatoprost volume of distribution

There was no significant systemic drug accumulation over time. Distribution Bimatoprost is moderately distributed into body tissues with a steady-state volume of distribution of 0.67 L/kg. In human blood, bimatoprost resides mainly in the plasma. Approximately 12% of bimatoprost remains unbound in human plasma.

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2018 Statistics

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Total savings $4,735,080

What is Bimatoprost

Bimatoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes. It binds to the prostanoid FP receptor.

Bimatoprost mechanism of action

Bimatoprost is believed to lower intraocular pressure (IOP) in humans by increasing outflow of aqueous humor through both the trabecular meshwork and uveoscleral routes. Bimatoprost reduces the pressure in the eye by mimicking the action of a naturally-occuring prostaglandin. Prostaglandins are a group of chemicals found in many places in the body. In the eye, they increase the drainage of the aqueous humour out of the eyeball. Bimatoprost is a synthetic compound related to one of the natural prostaglandins, and works by increasing the drainage of aqueous humour out of the eyeball. Bimatoprost may also lower the rate of aqueous formation in the eye. Both these effects decrease the pressure within the eye.

Dosage forms of Bimatoprost

DrugDosageQuantityPrice
Bimatoprost0.03%3mL Drops$38.00
Bimatoprost0.03%9mL Drops$49.90
Lumigan Eyedrops0.01%9mL Opthalmic Solution$42.95
Lumigan Eyedrops0.03%3mL Opthalmic Solution$22.85
Latisse0.03%3mL Ophalthalmic Solution$180.00
Latisse0.03%5mL Ophalthalmic Solution$244.00

Prescription Generics

true

International Brands

Apo-bimatoprost

Synonyms

(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1e,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide Bimatoprostum

Manufacturers

Apotex Inc

CAS number

155206-00-1

UNII

QXS94885MZ

State

solid

Affected organisms

Humans and other mammals

Indication of Bimatoprost

For the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.

Toxicity of Bimatoprost

In oral (by gavage) mouse and rat studies, doses up to 100 mg/kg/day did not produce any toxicity. This dose expressed as mg/msup2/sup is at least 70 times higher than the accidental dose of one bottle of bimatoprost for a 10 kg child.

RX24 Drugs Disclaimer: before buying a Bimatoprost on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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