Save up -80% on Botulinum Toxin Type A

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Botulinum Toxin Type A

Botox (100 – 200 unit/Vial)



* price without discount in nearest pharmacy. Price may vary.

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Botulinum Toxin Type A volume of distribution

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What is Botulinum Toxin Type A

Purified botulinum toxin from Clostridium botulinum, purified from culture via dialysis and acid precipitation.

Botulinum Toxin Type A mechanism of action

Botulinum Toxin Type A blocks neuromuscular transmission by binding to acceptor sites on motor or sympathetic nerve terminals, entering the nerve terminals, and inhibiting the release of acetylcholine. This inhibition occurs as the neurotoxin cleaves SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within nerve endings.

Dosage forms of Botulinum Toxin Type A

Injection, powder, lyophilized, for solutionintradermal; intramuscular100[USP’U]/1
Injection, powder, lyophilized, for solutionintradermal; intramuscular200[USP’U]/1
Powder for solutionintramuscular100 unit
Prescription Generics


International Brands



AbobotulinumtoxinA BoNT/A


Allergan, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Botulinum Toxin Type A

For the treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia. Also for the treatment of severe primary axillary hyperhidrosis that is inadequately managed with topical agents and for the treatment of strabismus and blepharospasm associated with dystonia, including benign essential blepharospasm or VII nerve disorders in patients 12 years of age and above. Also used cosmetically to temporarily improve the appearance of moderate-to-severe frown lines between the eyebrows (glabellar lines) as well as for the treatment of excessive underarm sweating.

Toxicity of Botulinum Toxin Type A

Based on toxicological studies, it has been estimated that the human LD50 ; by injection is approximately 2800 Units, equivalent to 28 individual vials of BOTOX (Botulinum Toxin Type A) Purified Neurotoxin Complex (100 Units) for a 70 kg adult. When injected intramuscularly, Botulinum Toxin Type A has been shown to be teratogenic or to have embryocidal effects in some animal species.

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