Save up -80% on Brentuximab vedotin

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Adcetris

$vial
price without discount in nearest pharmacy. Price may vary.

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We offer free Brentuximab vedotin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Brentuximab vedotin every time. What are you waiting for? Claim your prescription drug card now!

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Brentuximab vedotin volume of distribution

The steady state volume of distribution is 6-10 L.

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Brentuximab vedotin

Brentuximag vedotin or Adcetris is an antibody-drug conjugate that combines an anti-CD30 antibody and the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma. Brentuximag vedotin was approved in 2011, and in January 2012, the drug label was revised to include a boxed warning of progressive multifocal leukoencephalopathy and death following JC virus infection.

Brentuximab vedotin mechanism of action

Brentuximab vedotin is composed of 3 parts: a chimeric human-murine IgG1 that targets CD30, monomethyl auristatin E (MMAE),which is a microtubule disrupting agent, and a protease-susceptible linker that covalently links the antibody and MMAE. The IgG1 antibody enables brentuximab vedotin to target tumor cells expressing CD30 on their cell surface then brentuximab vedotin gets internalized into the cell. Once inside, the linker is cleaved releasing MMAE which binds disrupts the microtuble network.

Dosage forms of Brentuximab vedotin

FormRouteStrength
Injection, powder, lyophilized, for solutionintravenous50 mg/10.5mL
Powder for concentrate for solution for infusionIntravenous use50 mg
Powder for solutionintravenous50 mg

Prescription Generics

false

International Brands

Adcetris

Synonyms

cAC10-vcMMAE

Manufacturers

Seattle Genetics, Inc.

CAS number

914088-09-8

UNII

7XL5ISS668

State

solid

Affected organisms

Humans and other mammals

Indication of Brentuximab vedotin

Used in the treatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma.

Toxicity of Brentuximab vedotin

The most severe toxic reaction seen in patients is progressive multifocal leukoencephalopathy. Other toxicities include bone marrow suppression, infusion reactions, peripheral neuropathy, Stevens-Johnson syndrome, and tumor lysis syndrome.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Brentuximab vedotin on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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