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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Brimonidine

Apo-Brimonidine 0.2 % Solution



* price without discount in nearest pharmacy. Price may vary.

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Brimonidine volume of distribution

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What is Brimonidine

Brimonidine is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis. (Wikipedia) A topical gel formulation, marketed under the name Mirvaso, was FDA approved on August 2013 for the treatment of rosacea.

Brimonidine mechanism of action

Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric studies in animals and humans suggest that Brimonidine has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow. The topical gel reduces erythema through direct vasocontriction.

Dosage forms of Brimonidine

Liquidophthalmic0.2 %
Solutionophthalmic0.15 %
Solution/ dropsophthalmic1 mg/mL
Prescription Generics


International Brands



5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline Brimonidina


Allergan Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Brimonidine

The ophthalmic solution is indicated for patients with open-angle glaucoma or ocular hypertension to lower intraocular pressure. The topical gel is indicated for the treatment of persistent (nontransient) facial erythema of rosacea in adults 18 years or older.

Toxicity of Brimonidine

Oral LD sub50 /sub is 50 mg/kg in mice and 100 mg/kg in rats. Common adverse reactions of the topical gel formulation include erythema, flushing, skin burning sensation, and contact dermatitis.

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