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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Bumex

$17.0430 tablets/1 mg
Price with discount in nearest pharmacy. Price may vary.

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Bumetanide volume of distribution

The plasma pharmacokinetics of bumetanide revealed mean +/- standard deviation values for total clearance and apparent volume of distribution of 3.9 +/- 2.4 mL/min/kg and 0.74 +/- 0.54 L/kg, respectively. Patients excreted an average of 34% of each dose unchanged in the urine over 12 hours.

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What is Bumetanide

Bumetanide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. Bumetanide is a “water pill” (diuretic) that causes you to make more urine.

Bumetanide mechanism of action

Bumetanide interferes with renal cAMP and/or inhibits the sodium-potassium ATPase pump. Bumetanide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule. This results in excretion of sodium, chloride, and water and, hence, diuresis.

Dosage forms of Bumetanide

Injectionintramuscular; intravenous.25 mg/mL
Injection, solutionintramuscular; intravenous.25 mg/mL
Injection, solutionintranodal; intravenous.25 mg/mL

Prescription Generics


International Brands



3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid 3-Butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid


Nu Care Pharmaceuticals, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Bumetanide

For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.

Toxicity of Bumetanide

Overdosage can lead to acute profound water loss, volume and electrolyte depletion, dehydration, reduction of blood volume and circulatory collapse with a possibility of vascular thrombosis and embolism. Electrolyte depletion may be manifested by weakness, dizziness, mental confusion, anorexia, lethargy, vomiting and cramps. Treatment consists of replacement of fluid and electrolyte losses by careful monitoring of the urine and electrolyte output and serum electrolyte levels.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Bumetanide on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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