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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Butabarbital

Butisol sodium 30 mg tablet

$1.89tablet
price without discount in nearest pharmacy. Price may vary.

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We offer free Butabarbital coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Butabarbital every time. What are you waiting for? Claim your prescription drug card now!

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Butabarbital volume of distribution

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2018 Statistics

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Discount Cards 16,000+

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Total savings $4,735,080

What is Butabarbital

Butabarbital (trade name Butisol) is a prescription barbiturate sleep aid. Butabarbital has a particularly fast onset of effects and short duration of action compared to other barbiturates, which makes it useful for certain applications such as treating severe insomnia and relieving anxiety before surgical procedures; however it is also relatively dangerous particularly when combined with alcohol, and so is now rarely used, although it is still prescribed in some Eastern European and South American countries. Its short duration of action gives butabarbital a high abuse potential, comparable to secobarbital. (Wikipedia)

Butabarbital mechanism of action

Butabarbital binds at a distinct binding site associated with a Cl sup – /sup ionopore at the GABA sub A /sub receptor, increasing the duration of time for which the Cl sup – /sup ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. All of these effects are associated with marked decreases in GABA-sensitive neuronal calcium conductance (gCa). The net result of barbiturate action is acute potentiation of inhibitory GABAergic tone. Barbiturates also act through potent (if less well characterized) and direct inhibition of excitatory AMPA-type glutamate receptors, resulting in a profound suppression of glutamatergic neurotransmission.

Dosage forms of Butabarbital

FormRouteStrength
Tabletoral30 mg/1
Tabletoral100 mg
Tabletoral15 mg

Prescription Generics

false

International Brands

Butisol Sodium

Synonyms

5-Ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione 5-Ethyl-5-(1-methylpropyl)barbituric acid

Manufacturers

Meda Pharmaceuticals Inc.

CAS number

125-40-6

UNII

P0078O25A9

State

solid

Affected organisms

Humans and other mammals

Indication of Butabarbital

For short-term treatment of insomnia and anxiety disorders

Toxicity of Butabarbital

Signs of overdose include confusion (severe), decrease in or loss of reflexes, drowsiness (severe), fever, irritability (continuing), low body temperature, poor judgment, shortness of breath or slow or troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness (severe).

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