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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Butenafine

Mentax 1% cream



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What is Butenafine

Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes.

Butenafine mechanism of action

Although the mechanism of action has not been fully established, it has been suggested that butenafine, like allylamines, interferes with sterol biosynthesis (especially ergosterol) by inhibiting squalene monooxygenase, an enzyme responsible for converting squalene to 2,3-oxydo squalene. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Blockage of squalene monooxygenase also leads to a subsequent accumulation of squalene. When a high concentration of squalene is reached, it is thought to have an effect of directly kill fungal cells.

Dosage forms of Butenafine

Creamtopical1 %
Creamtopical1 g/100g
Creamtopical10 mg/g
Prescription Generics


International Brands

Dr. Scholl’s Athlete’s Foot Cream


(4-Tert-butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amine (4-Tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine


Schering Plough Healthcare Products Canada, A Division Of Schering Canada Inc.

CAS number






Affected organisms


Indication of Butenafine

For the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to iM. furfur /i, interdigital tinea pedis (athletersquo;s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to iE. floccosum /i, iT. mentagrophytes /i, iT. rubrum /i, and iT. tonsurans /i.

Toxicity of Butenafine

RX24 Drugs Disclaimer: before buying a Butenafine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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