Save up -80% on Butoconazole

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Gynazole-1

$109.841 applicator (5.8g) 2%
Price with discount in nearest pharmacy. Price may vary.

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We offer free Gynazole-1 coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Butoconazole every time. What are you waiting for? Claim your prescription drug card now!

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Butoconazole volume of distribution

Following vaginal administration of butoconazole nitrate vaginal cream, 2% to 3 women, 1.7% (range 1.3-2.2%) of the dose was absorbed on average.

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2018 Statistics

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Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Butoconazole

Butoconazole is an imidazole antifungal used in gynecology.

Butoconazole mechanism of action

The exact mechanism of the antifungal action of butoconazole is unknown, however, it is presumed to function as other imidazole derivatives via inhibition of steroid synthesis. Imidazoles generally inhibit the conversion of lanosterol to ergosterol via the inhibition of the enzyme cytochrome P450 14alpha;-demethylase, resulting in a change in fungal cell membrane lipid composition. This structural change alters cell permeability and, ultimately, results in the osmotic disruption or growth inhibition of the fungal cell.

Dosage forms of Butoconazole

FormRouteStrength
Creamvaginal100 mg/5g
Creamvaginal2 %

Prescription Generics

true

International Brands

Gynazole 1

Synonyms

Alant starch Butoconazol

Manufacturers

Perrigo New York Inc

CAS number

64872-76-0

UNII

0Q771797PH

State

solid

Affected organisms

Fungi, yeast and protozoans

Indication of Butoconazole

For the local treatment of vulvovaginal candidiasis (infections caused by Candida)

Toxicity of Butoconazole

Oral, rat: LD sub50 /sub = 1720 mg/kg.

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