Save up -80% on Cabozantinib
Note: this is a drug discount program, not an insurance plan.
2018 Price of Cabozantinib
* price without discount in nearest pharmacy. Price may vary.
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Cabozantinib volume of distribution
The volume of distribution is 349L.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Cabozantinib
Cabozantinib was approved in 2012 and is a non-specific tyrosine kinase inhibitor. It is marketed as Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. It’s label includes a black box warning of gastrointestinal perforations, fistulas, and hemorrhage. The FDA approved cabozantinib as Cabometyx for patients with advanced renal cell carcinoma in April 2016.
Cabozantinib mechanism of action
Cabozantinib inhibits specific receptor tyrosine kinases such as VEGFR-1, -2 and -3, KIT, TRKB, FLT-3, AXL, RET, MET, and TIE-2.
Dosage forms of Cabozantinib
Humans and other mammals
Indication of Cabozantinib
For the treatment of metastatic medullary thyroid cancer and for the treatment of patients with advanced renal cell carcinoma (RCC) who have received prior anti-angiogenic therapy.
Toxicity of Cabozantinib
Cabozantinib has a black box warning of serious gastrointestinal fistulas and perforations, and potentially fatal hemoptysis and gastrointestinal hemorrhage.
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