Save up -80% on Caffeine

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Caffeine

Butalb-apap-caff 50-500-40 tablet

$1.2

tablet

* price without discount in nearest pharmacy. Price may vary.

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Caffeine volume of distribution

* 0.8 to 0.9 L/kg (infants) * 0.6 L/kg (adults)

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What is Caffeine

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine’s most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes smooth muscle, stimulates cardiac muscle, stimulates diuresis, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide phosphodiesterases, antagonism of adenosine receptors, and modulation of intracellular calcium handling.

Caffeine mechanism of action

Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. This action was previously believed to be due primarily to increased intracellular cyclic 3 prime;,5 prime;-adenosine monophosphate (cyclic AMP) following inhibition of phosphodiesterase, the enzyme that degrades cyclic AMP. It is now thought that xanthines such as caffeine act as antagonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced “pounding” of the heart upon caffeine intake.

Dosage forms of Caffeine

DrugDosageQuantityPrice
Cafergot100/1mg60 Tablet$49.00
Anacin325mg100 Tablet$16.32
Mucinex600mg20 Extended Release 12Hour Tablet$43.00
Robitussin DM Extra Strength200mg100mL Syrup$26.00
Robitussin DM Cough Control100/15mg100mL Syrup$26.00
Prescription Generics

false

International Brands

(extra Strength) Acetaminophen, Caffeine 8mg Codeine Phosphate Caplets

Synonyms

1-methyltheobromine 1,3,7-Trimethyl-2,6-dioxopurine

Manufacturers

Stanley Pharmaceuticals, A Division Of Vita Health Products Inc.

CAS number

58-08-2

UNII

3G6A5W338E

State

solid

Affected organisms

Humans and other mammals

Indication of Caffeine

For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.

Toxicity of Caffeine

LD sub 50 /sub =127 mg/kg (orally in mice)

RX24 Drugs Disclaimer: before buying a Caffeine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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