Save up -80% on Caffeine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Caffeine
Butalb-apap-caff 50-500-40 tablet
|price without discount in nearest pharmacy. Price may vary.|
We offer free Caffeine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Caffeine every time. What are you waiting for? Claim your prescription drug card now!
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Caffeine volume of distribution
* 0.8 to 0.9 L/kg (infants) * 0.6 L/kg (adults)
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Caffeine
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine’s most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes smooth muscle, stimulates cardiac muscle, stimulates diuresis, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide phosphodiesterases, antagonism of adenosine receptors, and modulation of intracellular calcium handling.
Caffeine mechanism of action
Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. This action was previously believed to be due primarily to increased intracellular cyclic 3 prime;,5 prime;-adenosine monophosphate (cyclic AMP) following inhibition of phosphodiesterase, the enzyme that degrades cyclic AMP. It is now thought that xanthines such as caffeine act as antagonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced “pounding” of the heart upon caffeine intake.
Dosage forms of Caffeine
|Mucinex||600mg||20 Extended Release 12Hour Tablet||$43.00|
|Robitussin DM Extra Strength||200mg||100mL Syrup||$26.00|
|Robitussin DM Cough Control||100/15mg||100mL Syrup||$26.00|
(extra Strength) Acetaminophen, Caffeine 8mg Codeine Phosphate Caplets
Stanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Humans and other mammals
Indication of Caffeine
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Toxicity of Caffeine
LD sub 50 /sub =127 mg/kg (orally in mice)
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