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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Dovonex

$95.851 tube 60g/0.005%
price without discount in nearest pharmacy. Price may vary.

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Calcipotriol volume of distribution

Clinical studies with radiolabeled ointment indicate that approximately 6% (+3%, SD) of the applied dose of calcipotriene is absorbed systemically when the ointment is applied topically to psoriasis plaques or 5% (+2.6%, SO) when applied to normal skin.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.

Calcipotriol mechanism of action

The precise mechanism of calcipotriol in remitting psoriasis is not well-understood. However, it has been shown to have comparable affinity with calcitriol for the Vitamin D receptor, while being less than 1% as active as the calcitriol in regulating calcium metabolism. The Vitamin D receptor (VDR) belongs to the steroid/thyroid receptor superfamily, and is found on the cells of many different tissues including the thyroid, bone, kindney, and T cells of the immune system. T cells are known to play a role in psoriasis, and it is thought that the binding of calcipotriol to the VDR modulates the T cells gene transcription of cell differentiation and proliferation related genes.

Dosage forms of Calcipotriol

Dovonex Cream50mcg/g60g Cream$66.00
Dovonex Ointment50mcg/g90g Ointment$90.00
Dovonex Ointment50mcg/g120g Ointment$109.00
Dovonex Solution0.005%30mL Solution$35.00
Dovonex Solution0.005%60mL Solution$62.00

Prescription Generics


International Brands



Calcipotriene Calcipotriol


Impax Generics

CAS number






Affected organisms

Humans and other mammals

Indication of Calcipotriol

For the treatment of moderate plaque psoriasis in adults.

Toxicity of Calcipotriol

Topically applied calcipotriene can be absorbed in sufficient amounts to produce systemic effects. Elevated serum calcium has been observed with excessive use of calcipotriene.

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