Save up -80% on Calcipotriol
Note: this is a drug discount program, not an insurance plan.
2018 Price of Calcipotriol
Dovonex 0.005% cream
* price without discount in nearest pharmacy. Price may vary.
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Calcipotriol volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Calcipotriol mechanism of action
The precise mechanism of calcipotriol in remitting psoriasis is not well-understood. However, it has been shown to have comparable affinity with calcitriol for the Vitamin D receptor, while being less than 1% as active as the calcitriol in regulating calcium metabolism. The Vitamin D receptor (VDR) belongs to the steroid/thyroid receptor superfamily, and is found on the cells of many different tissues including the thyroid, bone, kindney, and T cells of the immune system. T cells are known to play a role in psoriasis, and it is thought that the binding of calcipotriol to the VDR modulates the T cells gene transcription of cell differentiation and proliferation related genes.
Dosage forms of Calcipotriol
|Dovonex Cream||50mcg/g||60g Cream||$66.00|
|Dovonex Ointment||50mcg/g||90g Ointment||$90.00|
|Dovonex Ointment||50mcg/g||120g Ointment||$109.00|
|Dovonex Solution||0.005%||30mL Solution||$35.00|
|Dovonex Solution||0.005%||60mL Solution||$62.00|
Humans and other mammals
Indication of Calcipotriol
For the treatment of moderate plaque psoriasis in adults.
Toxicity of Calcipotriol
Topically applied calcipotriene can be absorbed in sufficient amounts to produce systemic effects. Elevated serum calcium has been observed with excessive use of calcipotriene.
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