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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Invokana

$100.50

100mg

* price without discount in nearest pharmacy. Price may vary.

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Canagliflozin volume of distribution

Steady state, single IV infusion, healthy subject = 119 L. This high value suggests that cangliflozin is extensively distributed to tissue.

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What is Canagliflozin

Canagliflozin belongs to a new class of anti-diabetic drugs that works by inhibiting the sodium-glucose transport protein (SGLT2). This transport protein is found in the kidney and is responsible for reabsorbing glucose that has been filtered. FDA approved on March 29, 2013.

Canagliflozin mechanism of action

Sodium-glucose co-transporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Canagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, canagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose (RTG), and thereby increases urinary glucose excretion.

Dosage forms of Canagliflozin

DrugDosageQuantityPrice
Invokana100mg30 Tablet$100.50
Invokana300mg90 Tablet$515.00
Invokamet XR50/500mg60 Tablet$600.00
Invokamet50/500mg60 Tablet$600.00
Prescription Generics

false

International Brands

Invokamet

Synonyms

Canagliflozin anhydrous

Manufacturers

Janssen Inc

CAS number

842133-18-0

UNII

6S49DGR869

State

solid

Affected organisms

Humans and other mammals

Indication of Canagliflozin

Canagliflozin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Use in type 1 diabetes mellitus patients or in treatment of diabetic ketoacidosis is not recommended.

Toxicity of Canagliflozin

Most common adverse reactions associated with canagliflozin (5% or greater incidence): female genital mycotic infections, urinary tract infection, and increased urination.

RX24 Drugs Disclaimer: before buying a Canagliflozin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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