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Price of Capreomycin
Capastat sulfate 1 gm vial
* price without discount in nearest pharmacy. Price may vary.
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Capreomycin volume of distribution
What is Capreomycin
Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus. (PubChem)
Capreomycin mechanism of action
Little is known about capreomycin’s exact mechanism of action, but it is thought to inhibit protein synthesis by binding to the 70S ribosomal unit. Capreomycin also binds to components in the bacterial cell which result in the production of abnormal proteins. These proteins are necessary for the bacteria’s survival. Therefore the production of these abnormal proteins is ultimately fatal to the bacteria.
Dosage forms of Capreomycin
|Powder for solution||intramuscular; nil||1 g|
|Injection, powder, for solution||intramuscular; intravenous||1 g/1|
Capastat Pws Im 1g Vial
Eli Lilly Canada Inc
Enteric bacteria and other eubacteria
Indication of Capreomycin
Used in the treatment of tuberculosis in combination with other drugs.
Toxicity of Capreomycin
Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter’s syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD sub 50 /sub ) in mice was 514 mg/kg.
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