Save up -80% on Carboprost Tromethamine
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Price of Carboprost Tromethamine
Hemabate 250 mcg/ml ampul
* price without discount in nearest pharmacy. Price may vary.
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Carboprost Tromethamine volume of distribution
What is Carboprost Tromethamine
A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy. (PubChem)
Carboprost Tromethamine mechanism of action
Carboprost is a synthetic prostaglandin. It binds the prostaglandin E2 receptor, causing myometrial contractions, casuing the induction of labour or the expulsion of the placenta. Prostaglandins occur naturally in the body and act at several sites in the body including the womb (uterus). They act on the muscles of the womb, causing them to contract.
Dosage forms of Carboprost Tromethamine
|Injection, solution||intramuscular||250 ug/mL|
(15S)-15-Methyl-pgf2alpha tromethamine salt
(15S)-15-Methylprostaglandin F2alpha tromethamine
Pfizer Canada Inc
Humans and other mammals
Indication of Carboprost Tromethamine
For aborting pregnancy between the 13th and 20th weeks of gestation as calculated from the first day of the last normal menstrual period and in the following conditions related to second trimester abortion: 1. Failure of expulsion of the fetus during the course of treatment by another method; 2. Premature rupture of membranes in intrauterine methods with loss of drug and insufficient or absent uterine activity; 3. Requirement of a repeat intrauterine instillation of drug for expulsion of the fetus; 4. Inadvertent or spontaneous rupture of membranes in the presence of a previable fetus and absence of adequate activity for expulsion. Also for the treatment of postpartum hemorrhage due to uterine atony which has not responded to conventional methods of management.
Toxicity of Carboprost Tromethamine
Symptoms of overdose include irritation, nausea, vomiting, diarrhea, coughing, dyspnea, asthma, hypertension, flushing, and pyrexia.
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