Save up -80% on Carmustine

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Carmustine

Bicnu 100 mg vial



* price without discount in nearest pharmacy. Price may vary.

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Carmustine volume of distribution

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What is Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)

Carmustine mechanism of action

Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis). Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death.

Dosage forms of Carmustine

Powder for solutionintravenous100 mg
Waferintracavitary7.7 mg/1
Prescription Generics


International Brands



BCNU Bicnu (tn)


Heritage Pharmaceuticals Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Carmustine

For the treatment of brain tumors, multiple myeloma, Hodgkin’s disease and Non-Hodgkin’s lymphomas.

Toxicity of Carmustine

The oral LD sub 50 /sub s in rat and mouse are 20 mg/kg and 45 mg/kg, respectively. Side effects include leukopenia, thrombocytopenia, nausea. Toxic effects include pulmonary fibrosis (20-0%) and bone marrow toxicity.

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