Save up -80% on Carvedilol
Note: this is a drug discount program, not an insurance plan.
2018 Price of Carvedilol
Carvedilol 12.5 mg tablet
* price without discount in nearest pharmacy. Price may vary.
We offer free Carvedilol coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Carvedilol every time. What are you waiting for? Claim your prescription drug card now!
Carvedilol volume of distribution
* 115 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Carvedilol mechanism of action
Carvedilol is a racemic mixture in which nonselective beta-adrenoreceptor blocking activity is present in the S(-) enantiomer and alpha-adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilol’s beta-adrenergic receptor blocking ability decreases the heart rate, myocardial contractility, and myocardial oxygen demand. Carvedilol also decreases systemic vascular resistance via its alpha adrenergic receptor blocking properties. Carvedilol and its metabolite BM-910228 (a less potent beta blocker, but more potent antioxidant) have been shown to restore the inotropic responsiveness to Ca sup2+ /sup in OH sup- /sup free radical-treated myocardium. Carvedilol and its metabolites also prevent OH sup- /sup radical-induced decrease in sarcoplasmic reticulum Ca sup2+ /sup-ATPase activity. Therefore, carvedilol and its metabolites may be beneficial in chronic heart failure by preventing free radical damage.
Dosage forms of Carvedilol
Humans and other mammals
Indication of Carvedilol
For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin.
Toxicity of Carvedilol
Not expected to be toxic following ingestion.
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