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Price of Caspofungin
Cancidas iv 50 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Caspofungin volume of distribution
What is Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug, the first of a new class termed the echinocandins from Merck Co., Inc. It shows activity against infections with Aspergillus and Candida, and works by inhibiting .(1,3)-D-Glucan of the fungal cell wall. Caspofungin is administered intravenously.
Caspofungin mechanism of action
Caspofungin inhibits the synthesis of beta-(1,3)-D-glucan, an essential component of the cell wall of iAspergillus /i species and iCandida /i species. beta-(1,3)-D-glucan is not present in mammalian cells. The primary target is beta-(1,3)-glucan synthase.
Dosage forms of Caspofungin
|Injection, powder, lyophilized, for solution||intravenous||5 mg/mL|
|Injection, powder, lyophilized, for solution||intravenous||7 mg/mL|
|Powder for concentrate for solution for infusion||Intravenous use||50 mg|
(4R,5S)-5-((2-Aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(P-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
Merck Canada Inc
Aspergillis, Candida and other fungi
Indication of Caspofungin
For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
Toxicity of Caspofungin
Side effects include rash, swelling, and nausea (rare)
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