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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Caspofungin

Cancidas iv 50 mg vial

$405.25

vial

* price without discount in nearest pharmacy. Price may vary.

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Caspofungin volume of distribution

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What is Caspofungin

Caspofungin (brand name Cancidas worldwide) is an antifungal drug, the first of a new class termed the echinocandins from Merck Co., Inc. It shows activity against infections with Aspergillus and Candida, and works by inhibiting .(1,3)-D-Glucan of the fungal cell wall. Caspofungin is administered intravenously.

Caspofungin mechanism of action

Caspofungin inhibits the synthesis of beta-(1,3)-D-glucan, an essential component of the cell wall of iAspergillus /i species and iCandida /i species. beta-(1,3)-D-glucan is not present in mammalian cells. The primary target is beta-(1,3)-glucan synthase.

Dosage forms of Caspofungin

FormRouteStrength
Injection, powder, lyophilized, for solutionintravenous5 mg/mL
Injection, powder, lyophilized, for solutionintravenous7 mg/mL
Powder for concentrate for solution for infusionIntravenous use50 mg
Prescription Generics

false

International Brands

Cancidas

Synonyms

(4R,5S)-5-((2-Aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(P-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide 1-((4R,5S)-5-((2-Aminoethyl)amino)-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine)-5-((3R)-3-hydroxy-L-ornithine)-pneumocandin b0

Manufacturers

Merck Canada Inc

CAS number

162808-62-0

UNII

F0XDI6ZL63

State

solid

Affected organisms

Aspergillis, Candida and other fungi

Indication of Caspofungin

For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.

Toxicity of Caspofungin

Side effects include rash, swelling, and nausea (rare)

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