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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cefotaxime

Claforan 1 gm vial

$2.12

vial

* price without discount in nearest pharmacy. Price may vary.

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Cefotaxime volume of distribution

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What is Cefotaxime

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).

Cefotaxime mechanism of action

The bactericidal activity of cefotaxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cefotaxime shows high affinity for penicillin-binding proteins in the cell wall including PBP Ib and PBP III.

Dosage forms of Cefotaxime

FormRouteStrength
Injectionintravenous10 g/1
Injection, powder, for solutionintramuscular; intravenous1 g/1
Injection, powder, for solutionintramuscular; intravenous1 g/mL
Prescription Generics

true

International Brands

Cefotaxime

Synonyms

(6R,7R,Z)-3-(Acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo(4.2.0)oct-2-ene-2-carboxylic acid (6R,7R)-3-(Acetoxymethyl)-7-{((2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl)amino}-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid

Manufacturers

Wockhardt USA LLC.

CAS number

63527-52-6

UNII

N2GI8B1GK7

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Cefotaxime

Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery.

Toxicity of Cefotaxime

Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions. Oral rat LD sub50 /sub is over 20,000 mg/kg while intravenous rat LD sub50 /sub is over 7,000 mg/kg.

RX24 Drugs Disclaimer: before buying a Cefotaxime on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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