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Price of Cefotaxime
Claforan 1 gm vial
* price without discount in nearest pharmacy. Price may vary.
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Cefotaxime volume of distribution
What is Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Cefotaxime mechanism of action
The bactericidal activity of cefotaxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cefotaxime shows high affinity for penicillin-binding proteins in the cell wall including PBP Ib and PBP III.
Dosage forms of Cefotaxime
|Injection, powder, for solution||intramuscular; intravenous||1 g/1|
|Injection, powder, for solution||intramuscular; intravenous||1 g/mL|
Wockhardt USA LLC.
Enteric bacteria and other eubacteria
Indication of Cefotaxime
Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery.
Toxicity of Cefotaxime
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions. Oral rat LD sub50 /sub is over 20,000 mg/kg while intravenous rat LD sub50 /sub is over 7,000 mg/kg.
Disclaimer: before buying a Cefotaxime on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.