Save up -80% on Ceftolozane
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2018 Price of Ceftolozane
* price without discount in nearest pharmacy. Price may vary.
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Ceftolozane volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Ceftolozane
Ceftolozane is a semi-synthetic beta-lactam antibiotic. It was approved by the FDA in January 2015 for use in combination with tazobactam for the treatment of: -Complicated Intra-abdominal Infections, used in combination with metronidazole. -Complicated Urinary Tract Infections, including Pyelonephritis. Ceftolozane/tazobactam is marketed under the brand name Zerbaxa by Cubist Pharmaceuticals U.S, which effective January 22, 2015, is now a wholly owned subsidiary of Merck – Co., Inc.
Ceftolozane mechanism of action
Ceftolozane belongs to the cephalosporin class of antibacterial drugs. The bactericidal action of ceftolozane results from inhibition of cell wall biosynthesis, and is mediated through binding to penicillin-binding proteins (PBPs). Ceftolozane is an inhibitor of PBPs of iP. aeruginosa/i (e.g., PBP1b, PBP1c, and PBP3) and iE. coli/i (e.g., PBP3).
Dosage forms of Ceftolozane
|Injection, powder, lyophilized, for solution||intravenous|
|Powder for solution||intravenous|
Merck Sharp – Dohme Corp.
Gram negative and gram positive bacteria
Indication of Ceftolozane
-Complicated Intra-abdominal Infections, used in combination with metronidazole. -Complicated Urinary Tract Infections, including Pyelonephritis.
Toxicity of Ceftolozane
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