Save up -80% on Celecoxib
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Celebrex
|$16.26||30 capsules/20 0mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Celebrex coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Celecoxib every time. What are you waiting for? Claim your prescription drug card now!
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Celecoxib volume of distribution
Apparent volume of distribution at steady state (Vdss/F), 200 mg single dose, healthy subjects = 429 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Celecoxib
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex. In some countries, it is branded Celebra. Celecoxib is available by prescription in capsule form.
Celecoxib mechanism of action
The mechanism of action of celecoxib is believed to be due to inhibition of prostaglandin synthesis. Unlike most NSAIDs, which inhibit both types of cyclooxygenases (COX-1 and COX-2), celecoxib is a selective noncompetitive inhibitor of cyclooxygenase-2 (COX-2) enzyme. It binds with its polar sulfonamide side chain to a hydrophilic side pocket region close to the active COX-2 binding site. Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane.
Dosage forms of Celecoxib
Accel Pharma Inc
Humans and other mammals
Indication of Celecoxib
For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis
Toxicity of Celecoxib
Symptoms of overdose include breathing difficulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, and vomiting.
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What is Celebrex?
Celebrex is a nonsteroidal anti-inflammatory drug (NSAID). Celecoxib works by reducing hormones that cause inflammation and pain in the body.
Celebrex is used to treat pain or inflammation caused by many conditions, such as arthritis, ankylosing spondylitis, and menstrual pain. Celebrex is used for the treatment of juvenile rheumatoid arthritis in children and also for the treatment of hereditary polyps in the colon.
Celebrex can increase the risk of a fatal heart attack or stroke, especially if you use it for a long time or take high doses, or if you have heart disease. Do not use this medicine immediately before or after heart bypass surgery (coronary artery bypass surgery or CABG).
Celebrex can also cause stomach or intestinal bleeding, which can be fatal. These conditions may occur without warning when you use Celebrex, especially in older people. You should not take this medicine if you already have bleeding in your stomach or intestines.