Save up -80% on Celecoxib

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Celecoxib

Celebrex 50 mg capsule

$1.26

capsule

* price without discount in nearest pharmacy. Price may vary.

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Celecoxib volume of distribution

Apparent volume of distribution at steady state (Vdss/F), 200 mg single dose, healthy subjects = 429 L

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What is Celecoxib

Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex. In some countries, it is branded Celebra. Celecoxib is available by prescription in capsule form.

Celecoxib mechanism of action

The mechanism of action of celecoxib is believed to be due to inhibition of prostaglandin synthesis. Unlike most NSAIDs, which inhibit both types of cyclooxygenases (COX-1 and COX-2), celecoxib is a selective noncompetitive inhibitor of cyclooxygenase-2 (COX-2) enzyme. It binds with its polar sulfonamide side chain to a hydrophilic side pocket region close to the active COX-2 binding site. Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane.

Dosage forms of Celecoxib

DrugDosageQuantityPrice
Celecoxib100mg60 Capsule$18.85
Celecoxib200mg100 Capsule$51.00
Celebrex100mg120 Capsule$80.95
Celebrex200mg30 Capsule$51.30
Prescription Generics

false

International Brands

Accel-celecoxib

Synonyms

Celebrex Celecoxib

Manufacturers

Accel Pharma Inc

CAS number

169590-42-5

UNII

JCX84Q7J1L

State

solid

Affected organisms

Humans and other mammals

Indication of Celecoxib

For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis

Toxicity of Celecoxib

Symptoms of overdose include breathing difficulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, and vomiting.

RX24 Drugs Disclaimer: before buying a Celecoxib on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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